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Institute of Tissue Regeneration Engineering
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BULLENTIN
Medical Research Center
Medical Research Center
Institute of Tissue Regeneration Engineering
The Goal Mechanobiology
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Mechanobiology
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Mechanobiology Dental Medicine
Core Faculty Members
The Goal of Mechanobiology
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MRC Lecture Series
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Biomaterials and Interfaces
Nanotherapeutics and Delivery
Stem Cell Engineering
Neural Regeneration
Musculoskeletal Tissue Engineering
Tooth Repair and Dental Materials
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BULLENTIN
Medical Research Center
The Goal Mechanobiology
Research Center
Mechanobiology
research field
Research ability of
Mechanobiology Dental Medicine
Core Faculty Members
The Goal of Mechanobiology
Research Center
MRC Lecture Series
Feature Articles
Bioactive Materials (2024) Adaptive immunity of materials: Implications for tissue healing and regeneration
JH Lee*, SJ Shin, JH Lee, JC. Knowles, HH Lee, HW Kim*
Advanced Science (2024) Neural Tissue-Like, not Supraphysiological, Electrical Conductivity Stimulates Neuronal Lineage Specification through Calcium Signaling and Epigenetic Modification
Li YM, Ji Y, Meng YX, Kim YJ, Lee H, Kurian AG, Park JH, Yoon JY, Knowles JC, Choi Y, Kim YS, Yoon BE, Singh RK, Lee HH, Kim HW*, Lee JH*
Advanced Science (2024) Tissue Mechanics and Hedgehog Signaling Crosstalk as a Key Epithelial–Stromal Interplay in Cancer Development
Karunasagara S, Taghizadeh A, Kim SH, Kim SJ, Kim YJ, Taghizadeh M, Kim MY, Oh KY, Lee JH, Kim HS, Hyun J*, Kim HW*
Advanced Science (2024) Targeting Nuclear Mechanics Mitigates the Fibroblast Invasiveness in Pathological Dermal Scars Induced by Matrix Stiffening
Fu X, Taghizadeh A, Taghizadeh M, Li CJ, Lim NK, Lee JH, Kim HS*, Kim HW*
Nano-Micro Letters (2024) Nanozyme-Engineered Hydrogels for Anti-Inflammation and Skin Regeneration
Kurian AG, Singh RK, Sagar V, Lee JH, Kim HW*
Feature Articles @ITREN in 2018~2024 (최근 6년간 출간된 하이라이트 논문 46편)
ITREN
Advanced Science (2023) Cyclic stretch promotes cellular reprogramming process through cytoskeletal-nuclear mechao-coupling...
Park SM, Lee JH*, Ahn GS,..., Shim H*, Kim HW*
Trends in Biotechnology (2023) Advanced materials technologies to unravel mechanobiological phenomena
Kim HS, Taghizadeh A, Taghizadeh M, Kim HW*
Advanced Functional Materials (2023) Coordinated Biophysical Stimulation of MSCs via Electromagnetized Au-Nanofiber Matrix Regulates Cytoskeletal-to-Nuclear Mechanoresponses and Lineage Specification
Singh RK*, Kurian AG, Sagar V, ..., Lee JH*, Kim HW *
Bioactive Materials (2023) Double hits with bioactive nanozyme based on cobalt-doped nanoglass for acute and diabetic wound therapies through anti-inflammatory and pro-angiogenic functions
Mandakhbayar N, Ji Y, ..., Lee JH*, Kim HW*
Materials Today Bio (2023) Multifunctional dendrimer@nanoceria engineered GelMA hydrogel accelerates bone regeneration through orchestrated cellular responses
Kurian AG, Mandakhbayar N, Singh RK*, Lee JH*, Jin G, Kim HW*
Chemical Engineering Journal (2023) Electroconductive and mechano-competent PUCL@CNT nanohybrid scaffolds guiding neuronal specification
Li YM, Patel KD, Han YG, ... Lee JH*, Kim HW*
Biomaterials (2023) Mechano-modulation of T cells for cancer immunotherapy
Hyun J*, Kim SJ, Cho SD, Kim HW*
Progress in Materials Science (2023) Materials-based nanotherapeutics for injured and diseased bone
Lee CS, Sing RK, ... Kim HS*, Lee M*, Kim HW*
Advanced Healthcare Materials (2023) Delivery of Induced Neural Stem Cells Through Mechano-tuned Silk-collagen Hydrogels...
Davaa G, Hong JY, Lee JH,... Hyun JK*, Kim HW*
Biomaterials (2022) Nanoceria-GO-intercalated multicellular spheroids revascularize and salvage critical ischemic limbs through anti-apoptotic...
Bayaraa O, Dashnyam K, Singh RK,...Lee JH, Kim HW*
Matter (2022) Matrix-enabled mechanobiological modulation of osteoimmunology
Jung-Hwan Lee, Jae Hee Park, Jun Hee Lee, Hae-Hyoung Lee, Jonathan C Knowles, Hae-Won Kim
Biomaterials (2022) Chemically-induced osteogenic cells for bone tissue engineering and disease modeling
Yoon JY, Mandakhbayar N, Hyun J, ..., Lee JH*, Leong KW, Kim HW*
Bioactive Materials (2022) Dendritic cell-mimicking scaffolds for ex vivo T cell expansion
Kim HS, Ho TC, ..., Kim HW, Leong KW*
Advanced Healthcare Materials (2022) Mimicking Bone Extracellular Matrix: From BMP-2-Derived Sequences...
Oliver-Cervelló L, Martin-Gómez H, ...,Kim HW, Ginebra MP, Lee JH, Mas-Moruno C*
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UCL Eastman-Korea Joint Center
Feature Articles @ITREN in 2018~2024 (최근 6년간 출간된 하이라이트 논문 46편)
ITREN Bulletin-Vol-1 has been published
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News & Story
Featured as Back Cover in Advanced Science
Conductivity-Dependent Neuronal Specification In article number 2400586, Hae-Won Kim, Jung-Hwan Lee, and co-workers show that neural-tissue-like, low conductivity (0.02–0.1 S m–1) promotes neuronal differentiation via balanced calcium signaling and epigenetic changes, while supraphysiological, high conductivity (3.2 S m–1) causes apoptosis. This work reveals optimal conductivity's crucial role in neural interface design for tissue engineering and regenerative medicine.
2024-09-27
Featured as Inside Front Cover in Advanced Science Journal
Cancer Cells' Mastery of Their Environment Cancer cells actively reshape their surroundings. By releasing sonic hedgehog, they stiffen the extracellular matrix, enlisting stromal cells as allies. This increased stiffness heightens actomyosin cytoskeleton tension, activating oncogenic transcription factors and driving invasive tumor growth. More details can be found in article number 2400063 by Jeongeun Hyun, Hae-Won Kim, and co-workers.
2024-09-27
(2024.09) 2024 1st Semester Beomjeong Academic Thesis Award Research Encouragement Scholarship
ITREN student winning the Grand Prize at the BumJung Academic Awards on April 30, 2024. Xiangting Fu (PhD course, 7th semester): Best Excellence Award (최우수상)
2024-09-05
(2024.09. People) New members joined
Dr. SoonChul Heo (Left), and Dr. Chang Hyun Byon (Right) joined as new members of ITREN in September. Welcome!
2024-09-05
(2024.09) NRF Fundings earned by ITREN doctors
Two teams of ITREN doctors each received 3-year grants supported by the National Research Foundation of Korea. Title: Development of a Next-Generation Patch-Based Muscle Regeneration and Recovery Platform using Sportomics Researchers: Dr. Han-Sem Kim, Dr. Amal George Kurian Mentors: Prof. Hae-Won Kim, Prof. Ueon-Sang Shin Title: Development of Single-cell Microcapsules for Chemo-mechano Modulation of Osteoarthritis Researchers: Dr. Na-Hyun Lee, Dr. Hye Jin Hong Mentor: Prof. Hye-Sung Kim
2024-09-05
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2024-09-04
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2024-09-04
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2024-09-04
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Lecture Series
150. Columbia University, KAM LANCE CAMERON, Immune cell mechanobiology
149. Wonkwang University Prof. Seunghan OH, Titania Nanotube Applications in Dentistry
148. Seoul University, Prof. Seong-Joo Heo , Special Lecture on Dental Implants.
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