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ITREN

Core Faculty Members

Professor Hae-Won Kim Core Faculty
Institute of Tissue Regeneration Enginnering (ITREN)

Hae-Won Kim received his Ph.D from Seoul National University in 2002.

Following his graduation, he was a visiting scientist at the National Institute of Standards and Technology and then a Postdoctoral Fellow at the University College London (UCL) Eastman Dental in 2003-2004.

He was appointed as a professor in the College of Dentistry at Dankook University in 2005.

Currently, he is a full-time professor, director of the Institute of Tissue Regeneration Engineering (ITREN), and leader of Global Research Center for Regenerative Medicine, Mechanobiology Dental Medicine Research Center.

In addition, he serves as the editor-in-chief of the Journal of Tissue Engineering(IF: 8.2), associate editor of Frontiers in Bioengineering & Biotechnology, and edirorial board members in Biomaterials, Bioactive Materials, Med-X, etc.

He has published over 500 peer-reviewed papers with more than 37,000 citations (h index = 98).

His research interests are nanotherapeutics, stem cell engineering and biomaterials for regenerative medicine.

Google Scholar citation: https://scholar.google.com/citations?user=umYXC08AAAAJ&hl=ko

Degree

  • Bachelor Degree: From Seoul National University (1993.3-1997.2)
  • Masters Degree: From Seoul National Univ. (1997.3-1999.2)
  • Ph.D: From Seoul National Univ. (1999.3-2002.2)

Career

  • (2000-2002) - National Institute of Standards and Technology
  • (2002-2003) - Advanced Materials Research Center
  • (2003-2004) - Eastman Dental Institute of UCL)
  • (2004-2005) - Advanced Materials Research Center
  • (2005~Current) - Prof. Dankook University, Dental School
  • (2009~Current) - Prof. Nanobiomedical Science (Graduate School, in WCU program)
  • (2008~Current) - Director, Institute of Tissue Regeneration Engineering (ITREN)
  • (2015~Current) - Visiting Professor, UCL
  • (2015~Current) - Visiting Professor, Columbia University

Other

  • Editor In Chief : Journal of Tissue Engineering
  • Associate Editor : - Frontiers in Biotechnology and Bioengineering
  • Editorial Board Member : - Biomaterials - Bioengineering - Bioactive Materials - Mex-X

Publication Statistics

  • Total Publications - 510
  • Research Articles - 430
  • Review Articles - 80
  • Total Citation - 37,000
  • H-Index - 98

Selected Papers

  • [51] Materials-based nanotherapeutics for injured and diseased bone, Prog Mater Sci (2023)
  • [50] Electroconductive and mechano-competent PUCL@CNT nanohybrid scaffolds guiding neuronal specification of neural stem/progenitor cells, Chem Eng J (2023)
  • [49] Materials and extracellular matrix rigidity highlighted in tissue damages and diseases: 
  • Implication for biomaterials design and therapeutic targets, Bioact Mater (2023)
  • [48] Dendritic cell-mimicking scaffolds for ex vivo T cell expansion, Bioact Mater (2022)
  • [47] Highly efficient fabrication of functional hepatocyte spheroids by a magnetic system for the rescue of acute liver failure. Trend Mol Med (2023)
  • [46] Nanoceria-GO-intercalated multicellular spheroids revascularize and salvage critical ischemic limbs through anti-apoptotic and pro-angiogenic functions, Biomater (2023)
  • [45] Matrix-enabled mechanobiological modulation of osteoimmunology, Matter (2022)
  • [44] Chemically-induced osteogenic cells for bone tissue engineering and disease modeling, Biomaterials (2022)
  • [43] TLR4 downregulation by the RNA-binding protein PUM1 alleviates cellular aging and osteoarthritis. Cell Death Diff (2022)
  • [42] Leveraging cellular mechano-responsiveness for cancer therapy. Trend Mol Med (2022)
  • [41] Electricity auto- generating skin patch promotes wound healing process by activation of mechanosensitive ion channels. Biomaterials (2021)
  • [40] Spatiotemporal control of CRISPR/CAS9 editing. Signal Trans Target Ther  (2021)
  • [39] Optimally dosed nanoceria attenuates osteoarthritic degeneration of joint cartilage and subchondral bone. Chem Eng J (2021)
  • [38] Therapeutic tissue regenerative nanohybrids self-assembled from bioactive inorganic core / chitosan shell nanounits.  Biomaterials (2021)
  • [37] Antibacterial, proangiogenic, and osteopromotive nanoglass paste coordinates regenerative process following bacterial infection in hard tissue. Biomaterials (2021)
  • [36] Materials roles for promoting angiogenesis in tissue regeneration. Prog Mater Sci.(2020)
  • [35] Protein-reactive nanofibrils decorated with cartilage-derived decellularized extracellular matrix for osteochondral defects. Biomaterials (2020)
  • [34] Molecularly Imprinted Polymers and Electrospinning: Manufacturing Convergence for Next‐Level Applications. Adv Funct Mater (2020)
  • [33] Revascularization and limb salvage following critical limb ischemia by nanoceria-induced Ref-1/APE1-dependent angiogenesis. Biomaterials (2020)
  • [32] Hierarchical microchanneled scaffolds modulate multiple tissue-regenerative processes of immune-responses, angiogenesis, and stem cell homing. Biomaterials (2020).
  • [31] Anti-inflammatory actions of folate-functionalized bioactive ion-releasing nanoparticles imply drug-free nanotherapy of inflamed tissues. Biomaterials (2019).
  • [30] Role of nuclear mechanosensitivity in determining cellular responses to forces and biomaterials. Biomaterials (2019).
  • [29] Nanocements produced from mesoporous bioactive glass nanoparticles. Biomaterials (2018).
  • [28] Drug/ion co-delivery multi-functional nanocarrier to regenerate infected tissue defect. Biomaterials (2017).
  • [27] Silica-based multifunctional nanodelivery systems toward regenerative medicine. Mater Horizons (2017).
  • [26] Cerium oxide nanoparticles enhance functional recovery following spinal cord contusion in rats. Advanced Science (2017).
  • [25] CRISPR/Cas9-based genome editing for disease modeling and therapy: opportunities for non-viral delivery. Chem Rev (2017).
  • [24] Extra- and intra-cellular fate of nanocarriers under dynamic interactions with biology. Nano Today (2017).
  • [23] Promoting angiogenesis with mesoporous microcarriers through a synergistic action of delivered silicon ion and VEGF. Biomaterials (2017).
  • [22] Biomaterials control of pluripotent stem cell fate for regenerative therapy. Prog Mater Sci (2016).
  • [21] Magnetic nanocomposite scaffolds combined with static magnetic field in the stimulation of osteoblastic differentiation and bone formation. Biomaterials (2016)
  • [20] Gene delivery nanocarriers of bioactive glass with unique potential to load BMP2 plasmid DNA and to internalize into mesenchymal stem cells for osteogenesis and bone regeneration. Nanoscale (2016)
  • [19] Sol-gel based materials for biomedical applications. Prog Mater Sci (2016)
  • [18] Therapeutically-relevant aspects in bone repair and regeneration. Mater Today (2016)
  • [17] Generating iPSCs: Translating cell reprogramming science into scalable and robust biomanufacturing strategies. Cell Stem Cell (2015).
  • [16] Smart multifunctional drug delivery towards anticancer therapy harmonized in mesoporous nanoparticles. Nanoscale (2015).
  • [15] Multifunctional and stable bone mimic proteinaceous matrix for bone tissue engineering. Biomaterials (2015).
  • [14] Electrical stimulation by enzymatic biofuel cell to promote proliferation, migration and differentiation of muscle precursor cells. Biomaterials (2015).
  • [13] Sol-gel synthesis and electrospraying of biodegradable (P2O5)55-(Ca)30-(Na2O)15 glass nanospheres as a transient contrast agent for ultrasound stem cell imaging. ACS Nano (2015).
  • [12] Nano-bio-chemical braille for cells - the regulation of stem cells using bi-functional surfaces. Adv Funct Mater (2015).
  • [11] Naturally and synthetic smart composite biomaterials for tissue regeneration. Adv Drug Deliv Rev (2013).
  • [10] Biofunctionalized carbon nanotubes in neural regeneration: a mini-review. Nanoscale (2013).
  • [9] Capacity of mesoporous bioactive glass nanoparticles to deliver therapeutic molecules. Nanoscale (2012).
  • [8] Electrospun materials as potential platforms for bone tissue engineering. Adv Drug Deliv Rev (2009)
  • [7] Production and Potential of Bioactive Glass Nanofiber as a Next Generation Biomaterial. Adv Funct Mater (2006)
  • [6] Nanofiber Generation of Gelatin-Hydroxyapatite Biomimetic Nanofibers for Guided Tissue Regeneration. Adv Funct Mater (2005).
  • [5] Stimulation of osteoblast responses to biomimetic nanocomposites of gelatin-hydroxyapatite for tissue engineering scaffolds. Biomaterials 26;5221-230 (2005).
  • [4] Effect of fluoridation of hydroxyapatite in hydroxyapatite-polycaprolactone composites on osteoblast activity. Biomaterials 26:4395-4404 (2005).
  • [3] Hydroxyapatite / poly(e-caprolactone) composite coatings on hydroxyapatite porous bone scaffold for drug delivery. Biomaterials 25:1279-87 (2004).
  • [2] Fluor-hydroxyapatite sol-gel coating on titanium substrate for hard tissue implants. Biomaterials25:3351-8 (2004).
  • [1] Hydroxyapatite coatings on titanium substrate with titania buffer layer processed by sol-gel method. Biomaterials 25:2533-8 (2004).

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